With an alarming increase in the number of cancer patients and a variety of tumors, it is high time for intensive investigation on more efficient and potent anti-tumor agents.Though numerous agents have enriched the depileve easy clean literature, still there exist challenges, with the availability of different targets and possible cross-reactivity
A synthetic system links FeFe-hydrogenases to essential E. coli sulfur metabolism
Abstract Background FeFe-hydrogenases are the most active class of H2-producing enzymes known in nature and may have important applications in clean H2 energy production.Many potential uses are currently complicated by a crucial weakness: the active sites of all known FeFe-hydrogenases are irreversibly inactivated by O2.Results baseball scoreboards
Performance Evaluation of Underwater Wireless Optical Communications Links in the Presence of Different Air Bubble Populations
We experimentally evaluate click here the performance of underwater wireless optical communication (UWOC) links in the presence of different air bubbles.Air bubbles of different sizes and densities are generated by using an air pipe in conjunction with a submersible water pump of variable flow rate that helps break up large bubbles into smaller bub
The Cytoprotective and Cytotoxic Functions of Autophagy in Response to mTOR Inhibitors
The inhibitors of mammalian target of rapapmycin (mTOR), everolimus, temsirolimus and rapamycin, have a wide range of clinical utility; however, as is inevitably the case with other chemotherapeutic agents, resistance development constrains their effectiveness.One putative mechanism of resistance is the promotion of autophagy, which is a direct con
Constitutional Models of the Principle of Social Justice in African Countries: Comparative Legal Analysis
Based on the comparative legal analysis of the constitutions of African states, the article analyzes the constitutional models of the principle of social justice.The genesis of the Western legal understanding of the principle of social justice, the peculiarities of its reflection in the African legal culture are considered.Highlighting the Western